Basic Studies on the Apoptosis Mechanism of Trichoplusia ni cell line

  • Lee, Jong-Min (Department of Genetic Engineering, Kyung Hee University) ;
  • Sohn, Bong-Hee (Department of Sericulture & Entomology, NIAST, RD) ;
  • Kim, Yong-Soon (Department of Sericulture & Entomology, NIAST, RD) ;
  • Kang, Pil-Don (Department of Sericulture & Entomology, NIAST, RD) ;
  • Lee, Sang-Uk (Department of Sericulture & Entomology, NIAST, RD) ;
  • Chang, Seung-Jong (Department of Sericulture & Entomology, NIAST, RD) ;
  • Chung, In-Sik (Department of Genetic Engineering, Kyung Hee University)
  • Published : 2003.04.01

Abstract

To elucidate the apoptosis mechanism of Trichoplusia ni cell, fundamental studies for apoptosis induction and suppression were performed. Hygromycin B, a known inducer of apoptosis, started the inhibition of T ni cell growth at 200 ug/$m\ell$ concentration. Furthermore, at 400 $\mu\textrm{g}$/$m\ell$ concentration, DNA fragmentation was detected on day 2 of incubation. (omitted)

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