한국수의병리학회:학술대회논문집 (Proceedings of the Korean Society of Veterinary Pathology Conference)
- 한국수의병리학회 2003년도 추계학술대회초록집
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- Pages.46-46
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- 2003
Protective Effects of YCY against Hepatotoxicity Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD) in Rats
- Woon Kwon (College of Vet. Med., Chungbuk National Univ.) ;
- Chai, Hee-youl (College of Vet. Med., Chungbuk National Univ) ;
- Young min Cho (College of Vet. Med., Chungbuk National Univ) ;
- Park, Ehn-kyoung (College of Vet. Med., Chungbuk National Univ) ;
- Kim, Ik-soo (Department of Sericulture and Entomology, NIAS) ;
- Ryu, Kang-sun (Department of Sericulture and Entomology, NIAS) ;
- Hwang, Seock-Yeon (Dept. of Clinical Pathol., Chungbuk National Univ,. Hospita) ;
- Yun, Chi-Young (Department of Biology. Daejeon University) ;
- Kang, Jong-Koo (College of Vet. Med., Chungbuk National Univ.)
- 발행 : 2003.10.01
초록
Polychlorinated dibenzo-p-dioxins (PCDDs) are widespread, persistant, and highly toxic environmental pollutants. TCDD is the most potent congener among PCDDs and the most thoroughly investigated model compound of this class of chemicals. These compounds elicit a variety of common biochemical and toxic response, including specific binding to the cytosolic AHR [1] and induces a variety of biological response ranging from induction of cytochrome P-450 1A (CYP1A) to liver damage and cancer [2]. This study was carried out to investigate the protective effects of YCY, extract of a cricket, Gryllus bimaculatus, on hepatotoxicity in 6-week-old SD rat exposured to TCDD (omitted)
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