한국수의병리학회:학술대회논문집 (Proceedings of the Korean Society of Veterinary Pathology Conference)
- 한국수의병리학회 2003년도 추계학술대회초록집
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- Pages.42-42
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- 2003
Differential regulation of phospho-p38 and phospho-ERK by TCDD
- Kim, Ho-jun (College of Veterinary Medicine. Chungnam National University) ;
- Cho, Sung-whan (College of Veterinary Medicine. Chungnam National University) ;
- Son, Hwa-young (College of Veterinary Medicine. Chungnam National University) ;
- Yoon, Won-kee (Korea Research Institute of Bioscience and Biotechnolog) ;
- Jeong, Kyung-shik (College of Veterinary Medicine, Kyungppok National University) ;
- Ryu, Si-yun (College of Veterinary Medicine. Chungnam National University)
- 발행 : 2003.10.01
초록
The contamination of the environment with pollutants is one of the main problems of modern life, and the levels pollution in industrialized regions are giving raise to increased public concern. The mitogen-activated protein kinase (MAP kinase) are playa pivotal role in the regulation of important cellular functions by activation of specific signal transduction pathways from cell the surface to the nuclei. Three major subgroups of MAP kinases have been identified, and these comprise the extracellular signal-regulated kinase (ERK), the c-Jun amino-terminal kinase (JNK), and the p38 MAP kinases [1-3]. Herein, we investigated the effect of regulation of phospho-JNK (p-JNK), phospho-p38 (p-p38) and phospho-ERK (p-ERK) by TCDD. (omitted)
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