Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.195-195
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- 2003
Inhibition of Atherosclerotic Lesion by KR-31378 in LDL Receptor Null Mice
- Kim, Jiyun (KRIBB) ;
-
Nam, Ki-Hoan
(KRIBB)
;
- Choi, Jae-Hoon (KRIBB) ;
- Kim, Hyoung-Chin (KRIB) ;
- Yang, Sung-Don (KRCT) ;
- Kang, Joo-Hyung (KRIBB) ;
- Ryu, Young-Han (KRIBB) ;
- Kim, Eun-Young (KRIBB) ;
- Kim, Sun-Ok (AgroPharma Research Institute, Dongbu Hannong Chemical Co., Ltd.) ;
- Yoo, Sung-Eun (KRCT) ;
- Oh, Goo-Taeg (KRIBB)
- Published : 2003.10.01
Abstract
The recruitment and infiltration of monocytes into the artery wall is a crucial early step in atherogenesis. KR-31378 has been shown to be a neuroprotective agent in rat brain via its potent antioxidant and antiapoptotic actions. Here, we report the effects of this compound on atherogenesis, and some possible mechanisms of action.(omitted)