Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.184-184
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- 2003
Enu is a Powerful Mutagen for Development Mutant Mice -Sixty-Six Mutants From Enu Mutagenesis Program in Kit/Krict-
- Seokjoo Yoon (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Cho, Kyu-Hyuk (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Cho, Jae-Woo (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Lee, Phil-Soo (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Kim, Yang-Eon (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Cha, Dal-Sun (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
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Park, Han-Jin
(Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology)
;
- Kang, Min-Sung (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology) ;
- Nam, Yoon-Yi (Laboratory of Toxicogenomics, Mutant Mouse Development Laboratory (NRL 2000), Korea Institute of Toxicology, Korea Research Institute Chemical of Toxicology)
- Published : 2003.10.01
Abstract
ENU(ethylnitrosourea) mutagenesis has been carrying out since 1999 in Korea Institute of Toxicology (KIT), Korea Research Institute Chemical of Technology (KRlCT). We have chosen BALB/c and C57BL/6 and screened for dominant and recessive mutants. Four hundred and twenty one males(GO) have been injected with ENU, 150, 200, 250 and 300 mg/kg body weight, twice, one week apart.(omitted)