Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.167-167
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- 2003
Effects of Rhus Verniciflua Strokes Extracts snd its Components on the Proliferation, Collagen Synthesis, and the Mrna Level of Hepatic Fibrosis Related Proteins in Rat Hepatic Stellate Cells
- Jung, Seung-Hyun (School of Lifesciences and Biotechology, Korea University) ;
- Kim, Jeong-Ran (School of Lifesciences and Biotechology, Korea University) ;
- Na, Chun-Soo (Lifetree Biotech Co., Ltd.) ;
- Park, Bum-Rak (Lifetree Biotech Co., Ltd.) ;
- Yoon, Sun-Young (Lifetree Biotech Co., Ltd.) ;
- Park, Young-In (School of Lifesciences and Biotechology, Korea University) ;
- Dong, Mi-Sook (School of Lifesciences and Biotechology, Korea University)
- Published : 2003.10.01
Abstract
Hepatic stellate cells (HSC) and the derived myofibroblasts are known to playa central role in liver fibrosis. Rhus verniciflua Strokes (RVS) has traditionally been used in Korea herbal medicine for a stomachic tonic. In this study, we observed the effect of RVS acetone extract (Ra) on the proliferation, the collagen synthesis, and hepatic fibrosis related proteins mRNA levels in HSC-T6 cells which is a fully acivated rat hepatic stellate cell line.(omitted)