한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2003년도 추계학술대회
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- Pages.167-167
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- 2003
Effects of Rhus Verniciflua Strokes Extracts snd its Components on the Proliferation, Collagen Synthesis, and the Mrna Level of Hepatic Fibrosis Related Proteins in Rat Hepatic Stellate Cells
- Jung, Seung-Hyun (School of Lifesciences and Biotechology, Korea University) ;
- Kim, Jeong-Ran (School of Lifesciences and Biotechology, Korea University) ;
- Na, Chun-Soo (Lifetree Biotech Co., Ltd.) ;
- Park, Bum-Rak (Lifetree Biotech Co., Ltd.) ;
- Yoon, Sun-Young (Lifetree Biotech Co., Ltd.) ;
- Park, Young-In (School of Lifesciences and Biotechology, Korea University) ;
- Dong, Mi-Sook (School of Lifesciences and Biotechology, Korea University)
- 발행 : 2003.10.01
초록
Hepatic stellate cells (HSC) and the derived myofibroblasts are known to playa central role in liver fibrosis. Rhus verniciflua Strokes (RVS) has traditionally been used in Korea herbal medicine for a stomachic tonic. In this study, we observed the effect of RVS acetone extract (Ra) on the proliferation, the collagen synthesis, and hepatic fibrosis related proteins mRNA levels in HSC-T6 cells which is a fully acivated rat hepatic stellate cell line.(omitted)