Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.163-163
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- 2003
Inhalation Delivery of Nano-Aerosol Containing PEI-glucose-PTEN Complex Induced Change of Protein Translation in Kras Knock-Qut Lung Cancer Model Mice
- Kim, H. W. (Laboratory of Toxicology, College of Veterinary Medicine, Laboratory of Biomedical Polymer and Tissue Engineering, College of Agricultural Biotechnology, Seoul National University) ;
- Park, I. K. (Laboratory of Toxicology, College of Veterinary Medicine, Laboratory of Biomedical Polymer and Tissue Engineering, College of Agricultural Biotechnology, Seoul National University) ;
- C. S. Cho (Laboratory of Toxicology, College of Veterinary Medicine, Laboratory of Biomedical Polymer and Tissue Engineering, College of Agricultural Biotechnology, Seoul National University) ;
- M. H. Cho (Laboratory of Toxicology, College of Veterinary Medicine, Laboratory of Biomedical Polymer and Tissue Engineering, College of Agricultural Biotechnology, Seoul National University)
- Published : 2003.10.01
Abstract
Difficulties of long-tenn survival of lung cancer patients treated with conventional therapies require the need for novel approaches and gene therapy holds promise in this area. Several genes are known to have anti-tumor activities and have been used as a gene of delivery, however, a number of problems such as efficiency, specificity of the gene delivery hinder the application of gene therapy.(omitted)