Establishment Percutaneous Administration Method in Beagle Dog

  • Han, Su-Cheol (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Bae, Ju-Hyun (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Cha, Shin-Woo (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Jiang, Cheng-Zhe (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Tarumoto Y. (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Kim, Choong-Yong (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology) ;
  • Chung, Moon-Koo (Non-rodent and primate team, Toxicology division, Korea Institute of Toxicology)
  • Published : 2003.10.01

Abstract

The primary routes of drug administration include oral, intramuscular, subcutaneous and intravenous dosing for toxicological risk assessment purpose in dog. There has been an increase applying transdermal patches as an alternate method for systemic delivery. The present study was performed to establish the transdermal delivery method of medicated ointment, liquid and powder material to beagle dog.(omitted)

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