Assessment of cytokine producing cells to discriminate between allergen and irritant in the local lymph node assay

  • Lee, Jong-Kwon (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Byun, Jung-A (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Park, Seung-Hee (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Kim, Hyung-Soo (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Park, Jae-Hyun (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Ryu, Mi-Hyun (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Park, Han-Jin (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Juno H. Eom (Immunotoxicology Division, National Institute of Toxicological Research, KFDA) ;
  • Oh, Hye-Young (Immunotoxicology Division, National Institute of Toxicological Research, KFDA)
  • Published : 2003.10.01

Abstract

A murine local lymph node assay(LLNA) has been developed as an alternative method to guinea pig maximization test for contact sensitization potential. This study was carried out to investigate the potential use of cytokine producing cells to discriminate between allergens and irritant in the LLNA.(omitted)

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