Anti- inflammatory mechanism of melittin, a component of bee venom in Raw 264.7 cells and Synoviocyte

  • Park, Hye-Ji (College of Pharmacy, Chungbuk National University) ;
  • Kim, Kee-Hyun (Department of Oriental medicine, Graduate School of Kyungwon University) ;
  • Lee, Chung-Ou (College of Pharmacy, Chungbuk National University) ;
  • Lee, Sun-Young (College of Pharmacy, Chungbuk National University) ;
  • Lee, Seung-Ho (College of Pharmacy, Chungbuk National University) ;
  • Son, Dong-Ju (College of Pharmacy, Chungbuk National University) ;
  • Yun, Yeo-Pyo (College of Pharmacy, Chungbuk National University) ;
  • Oh, Ki-Wan (College of Pharmacy, Chungbuk National University)
  • 발행 : 2003.10.01

초록

Bee Venom (BV) has been treated in inflammatory diseases such as rheumatoid arthritis (RA). Bee venom contains several biologically active non-peptide substances as well as two major known peptides; the hemolytic peptide melittin (50%) and the neurotoxic peptide apamin, and a number of minor peptides.(omitted)

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