Safety evaluation of gene therapy - a case study of naked DNA product

  • Ahn, Byung-Ok (Research Institute of Dong-A Pharmaceutical CO., LTD.)
  • Published : 2003.10.01

Abstract

Gene therapy is a medical intervention based on modification of the genetic material of living cells. Gene transfer usually conducted using bacterial plasmid DNA and/or virus vector to express a specific protein. Gene transfer medicinal products classified as naked nucleic acid, complexed nucleic acid or non-viral vectors, viral vector, and genetically modified cells according to biological origin.(omitted)

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