13 Weeks Repeated-Dose Toxicity Studies 1,3-dichloro-2-propanol in Rats

  • Oh, Jae-Ho (Department of General Toxicology, National Institute of Toxicological Research) ;
  • Shin, Dong-Hwan (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Kim, Sheen-Hee (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Hwang, Myung-Sil (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Lim, Chul-Joo (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Yum, Young-Na (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Yang, Ki-Hwa (Department of General Toxicology, National Institute of Toxicological Researc) ;
  • Cho, Dae-Hyun (Department of General Toxicology, National Institute of Toxicological Research)
  • Published : 2003.05.01

Abstract

1,3-Dichloro-2-propanol(1,3-DCP), together with 3-monochloro-propane -1,2-diol(3-MCPD), is a well-known contaminant of acid-hydrolysed vegetable protein. 1,3-DCP has also been found to occur in a range of other foods and ingredients, most notable in soy sauce. The objective of the study was to determine the toxicity of the 1,3-DCP in the rat following oral administration for 13 weeks. (omitted)

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