Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.05a
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- Pages.46-46
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- 2003
Characterization of antihypertensive effect of I. sinclairii and its Genotoxic evaluation in 3 sets of mutagenicity tests
- Ahn, Mi-Young (Dept. Serio ＆ Ent., NIAST, RDA) ;
- Jung, Yi-Sook (Div. of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
- Lee, Bo-Kyung (Div. of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
- Kim, Chan-Sik (Div. of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
- Moon, Chang-Hyun (Div. of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
- Kim, In-Sun (Dept. Physiol. School of Medicine, Ajou University) ;
- Lee, Byung-Mu (Dept. Physiol. School of Medicine, Ajou University) ;
- Gyu, Kang-Sun (Dept. Physiol. School of Medicine, Ajou University) ;
- Kim, Ik-Soo (Dept. Serio ＆ Ent., NIAST, RDA) ;
- Kim, Jin-Won (Dept. Serio ＆ Ent., NIAST, RDA)
- Published : 2003.05.01
Abstract
The present study examined the effect of alcohol extract of Isaria sinclairii on blood pressure in spontaneously hypertensive rats (SHR). The blood pressure and heart rate were measured after treatment of alcohol extract of Isaria sinclairii by indirect tail cuff method and direct in vivo model. Male SHR were treated with extracts for 2 or 4 weeks starting at 12 weeks of age. (omitted)
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