한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2003년도 춘계학술대회 논문집
- /
- Pages.36-37
- /
- 2003
cDNA Microarray gene expression profiling of hydroxyurea, paclitaxel and p-anisidine that are genotoxic compounds with differing tumorigenicity results
- Lee, Michael (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) ;
- Jung Kwon (Korea Institute of Toxicology, Korea Research Institute of Chemical Technolog) ;
- Kim, Se-Nyun (Digital Genomics, Inc. B156 Yonsei Engineering Research Comple) ;
- Kim, Ja-Eun (Digital Genomics, Inc. B156 Yonsei Engineering Research Comple) ;
- Koh, Woo-Suk (Korea Institute of Toxicology, Korea Research Institute of Chemical Technolog) ;
- Song, Chang-Woo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technolog) ;
-
Chung, Moon-Koo
(Korea Institute of Toxicology, Korea Research Institute of Chemical Technology)
- 발행 : 2003.05.01
초록
The potential application of toxicogenomics to predictive toxicology has been discussed widely, but the utility of the approach remains largely unproven. Using cDNA microarrays, we have compared the gene expression profiles produced in mouse lymphoma cells by three genotoxic compounds, hydroxyurea (a carcino- gen), p-anisidine (a noncarcinogen) and paclitaxel (carcinogenicity unknown). (omitted)
키워드