Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)
- 2003.09a
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- Pages.698-699
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- 2003
PROTECTIVE EFFECT OF DA-3711, A NEW ANTIWRINKLE AGENT, AGAINST UVB-INDUCED SKIN DAMAGE IN HAIRLESS MICE MODEL
- Kim, J. M. (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Y. S. Sohn (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- K. K. Kang (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Lee, E. D. (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Lee, M. Y. (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- B. O. Ahn (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Lee, J. H. (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- J. W. Kwon (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Kim, W. B. (Research Laboratories, Dong-A Pharm. Co. Ltd.)
- Published : 2003.09.01
Abstract
DA-3711 is a novel, anti wrinkle agent containing growth factors derived from human skin culture. In this study, effect of topical application of DA-3711 on chronic ultraviolet B (UVB)-induced skin damage was evaluated in hairless mice model. Exposure to UVB for 8 weeks induced apparent wrinkles on the back skin of the mice. The dorsal surfaces were exposed to UVB for a further 8 weeks, during which the surfaces where treated daily by topically application of a lotion containing either 35％ or 70％ of DA-3711. For comparison, lotion base, lotion base containing Cylasphere Retinol(equation omitted) (2500 I.U., Coletica) and NouriCe
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