Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)
- 2003.09a
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- Pages.630-644
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- 2003
Modified SOD for Cosmeceuticals
- Kang, Nae-Gyu (C.I Center, LG Household ＆ Health Care) ;
- Lim, Jun-Man (C.I Center, LG Household ＆ Health Car) ;
- Chang, Min-Youl (C.I Center, LG Household ＆ Health Car) ;
- Park, Sun-Gyoo (C.I Center, LG Household ＆ Health Car) ;
- Cho, Wan-Goo (C.I Center, LG Household ＆ Health Car) ;
- Kang, She-Hoon (C.I Center, LG Household ＆ Health Car) ;
- Park, Soo-Young (Deparment of Genetic Engineering, Division of Life Sciences, Hallym University)
- Published : 2003.09.01
Abstract
A human Cu, Zn-superoxide dismutase (Cu, Zn-SOD) was fused with a Tat PTD of HIV-1 to produce a novel anti-aging ingredient, Tat-SOD for cosmeceuticals. Test of stability and evaluation of transduction efficacy and enzymatic activity suggest Tat-SOD is an effective active ingredient for anti-aging treatment.
Keywords
- transcriptional transactivator (Tat);
- protein transduction domain (PTD);
- aging;
- peptide;
- cosmeceuticals;
- superoxide dismutase (SOD);
- delivery;
- reactive oxygen species(ROS);
- human immunodeficiency virus (HIV)