Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)
- 2003.09a
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- Pages.520-539
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- 2003
A NEW MELANOGENESIS INHIBITOR FROM INGA ALBA (SW.) WILLD.
- Danoux, L. (Laboratoires Serobiologiques, Division de Cognis France) ;
- Henry, F. (Laboratoires Serobiologiques, Division de Cognis Franc) ;
- Moser, P. (Laboratoires Serobiologiques, Division de Cognis Franc) ;
- lGillon, V. (Laboratoires Serobiologiques, Division de Cognis Franc) ;
- Moretti, C. (Institut de Recherche pour le Developpement (IRD)) ;
- Pauly, G. (Laboratoires Serobiologiques, Division de Cognis France)
- Published : 2003.09.01
Abstract
By using sequentially efficacy tests based on tyrosinase, the key enzyme of melanogenesis, then a cell line of melanocytes cultured in vitro, we have been able to detect the whitening potential of a plant extract and then to develop a new whitening Active Ingredient whose the whitening potential was confirmed on cultured melanocytes. Through a phytochemical approach, it seems that the whitening potential could be due to the "tannin" fraction of plant extract. A complementary work is planned to explain more precisely which fractions are responsible for the whitening potential and a clinical test is in progress on 30 Asian skin type volunteers to show the whitening efficacy on human volunteers.