A stydy on the whitening substrate of natural products

  • Park, S. S. (Drug Evaluation Department, Korea Food & Drug Administration) ;
  • Kim, W. H. (Drug Evaluation Department, Korea Food & Drug Administratio) ;
  • K. H. Kong (Department of Chemistry, College of Natural Science, Chung-Ang Universit) ;
  • S. H. Cho (Department of Chemistry, College of Natural Science, Chung-Ang Universit) ;
  • S. J. Jang (Drug Evaluation Department, Korea Food & Drug Administration)
  • Published : 2003.09.01

Abstract

To investigate the potency of some natural extracts as skin whitening agents, in this study, 25 natural plants were prepared from natural sources including medicinal plants, such as Angelica dahurica using methylene dichloride, ethyl acetate, n-butyl alcohol, and water as the extraction and/or the partitioning solvents. These natural extracts were subsequently subjected to in-vitro DOPA auto-oxidation test in the media containing human or mushroom tyrosinase as the oxidation promoting enzymes. Most of the extracts showed relatively higher enzyme inhibition(omitted)

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