Development of Biological Cell Manipulation System using Visual Tracking Method

  • Lee, Geunho (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Kang, Hyun-Jae (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Kwon, Sang-Joo (Microsystem Research Center, Korea Institute of Science and Technology (KIST)) ;
  • Park, Gwi-Tae (Dept. of Electrical Engineering, Korea University) ;
  • Kim, Byungkyu (Microsystem Research Center, Korea Institute of Science and Technology (KIST))
  • Published : 2003.07.01

Abstract

Conventionally, biological manipulations have been performed manually with long training and pretty low success rates. To overcome this problem, a novel biological manipulation system has been developed to manipulate biological cells without any interference of a human operator, In this paper, we demonstrate a development of tole-autonomous Cell Manipulation System (CMS) using an image processing at a remote site. The CMS consists of two manipulators, a plane stage, and an optical microscope. We developed deformable template-model-matching algorithm for micro objects and pattern matching algorithm of end effect for these manipulators in order to control manipulators and the stage. Through manipulation of biological cells using these algorithms, the performance of the CMS is verified experimentally.

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