한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)

한국생물물리학회 (The Korean Biophysical Society)
권호 표지

The fluctuation and the rigidity study of F-actin filaments in a confined space

  • Park, Myung-Chul (Department of Physics, KAIST(Korea Advanced Institute of Science and Technology), MRL(Materials Research Laboratory) ＆ Materials department ＆ Physics department, University of California at Santa Barbara) ;
  • Youli Li (MRL(Materials Research Laboratory) & Materials department & Physics department, University of California at Santa Barbara) ;
  • Cyrus R. Safinya (MRL(Materials Research Laboratory) & Materials department & Physics department, University of California at Santa Barbara) ;
  • Kim, Mahn-Won (Department of Physics, KAIST(Korea Advanced Institute of Science and Technology), MRL(Materials Research Laboratory) ＆ Materials department ＆ Physics department University of California at Santa Barbara)
  • 발행 : 2003.06.01
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초록

Filamentous actin (F-actin) is a two stranded long helix that performs structural function in eukaryotic cells. F-actin had been assembled from Alexa-labeled G-actin and had been confined in microchannel. The fluctuation of single filaments was observed by fluorescence optical microscopy. We measured Tangent-tangent Correlation Function G(s) (where s is the distance along the contour of the chain), which tells us the confining wall effect of wormlike semi-flexible polymers as well as the flexural rigidity, such as persistence length.

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