Apoptosis by Direct Current Treatment in Tumor Cells and Tumor Tissues

  • Kim, H. B. (Institute of Biomedical Eng., Solco Biomedical) ;
  • S. B. Sim (Department of Chest & Cardiovascular Surgery, Catholic University) ;
  • S. Ahn (Institute of biomedical Eng., Solco Biomedical, School of Physics, of Seoul National University)
  • 발행 : 2003.06.01

초록

Electric field induces cell fusion, electroporation on biological cells, including apoptosis. Apoptosis is expressed in a series of natural enzymatic reactions for the natural elimination of unhealthy, genetically damaged, or otherwise aberrant cels that are not needed or not advantageous to the well-being of the organism. Its markers involve cell shringkage, activation of intracellular caspase proteases, externalization of phosphatidylserine at the plasma membrane, and fragmentation of DNA.

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