한국발생생물학회:학술대회논문집 (Proceedings of the Korean Society of Developmental Biology Conference)
- 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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- Pages.97-97
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- 2003
Human Embryonic Stem Cells Experience a Typical Apoptotic Process upon Oxidative Stress
- Lee, Gun-Soup (Maria Infertility Hospital Medical Institute/Maria Biotech) ;
- Lee, Young-Jae (Maria Infertility Hospital Medical Institute/Maria Biotech) ;
- Kim, Eun-Young (Maria Infertility Hospital Medical Institute/Maria Biotech) ;
- Park, Se-Pill (Maria Infertility Hospital Medical Institute/Maria Biotech) ;
- Lim, Jin-Ho (Maria Infertility Hospital)
- 발행 : 2003.10.01
초록
Embryonic stem (ES) cells, derived from preimplantation embryos, are able to differentiate into various types of cells consisting the whole body, or pluripotency. In addition to the plasticity, ES cells are expected to be different from terminally differentiated cells in very many ways, such as patterns of gene expressions, ability and response of the cells in confronting environmental stimulations, metabolism, and growth rate. As a model system to differentiate these two types of cells, human ES (hES, MB03) cells and terminally differentiated cells (HeLa), we examined the ability of these two types of cells in confronting a severe oxidative insult, that is