Relationship between nitric oxide and heme-oxygenase in human pulp cells

Heme oxygenase(HO) is a microsomal enzyme, widely distributed in mammalian tissues, which has a major role in heme metabolism. The role of HO in different tissues has not, as yet, been fully characterized, but it is becoming evident that it is involved in a variety of cellular regulatory and protective mechanism. Therefore, in this report, we confirmed the idea of whether the presence of HO in human pulpal cell, and HO can be a principal mechanism of nitric oxide(NO) mediated pulpal cell damage, by adding a deprivation of NO and to gain clinical relationship. We also accessed the effects of HO in pulpal cells treated with hydrogen.(omitted)