한국응용약물학회:학술대회논문집 (Proceedings of the Korean Society of Applied Pharmacology)
- 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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- Pages.114-114
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- 2003
Ginsenoside-Rb1 Acts as a Weak Estrogen Receptor Agonist Independent of Ligand Binding.
- Park, Wan-Kyu (Department of Bioscience and Biotechnology, Sejong University) ;
- Jungyoon Cho (Department of Bioscience and Biotechnology, Sejong University) ;
- Lee, Young-Joo (Department of Bioscience and Biotechnology, Sejong University)
- 발행 : 2003.11.01
초록
Ginseng is a medicinal herb widely used in Asian countries, and its pharmacological effects has been demonstrated in various systems such as cardiovascular, central nervous, and endocrine systems. Its effects are mainly attributed to the ginsenosides. We hypothesize that a component of Panax ginseng, ginsenoside-Rbl, acts by binding to estrogen receptor. We have investigated the estrogenic activity of ginsenoside-Rbl in a transient transfection system using estrogen receptors
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