한국응용약물학회:학술대회논문집 (Proceedings of the Korean Society of Applied Pharmacology)

한국응용약물학회 (The Korean Society of Applied Pharmacology)
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뇌신경행동에 미치는 $\mu$-opioid 수용체의 역할

Role of $\mu$-Opioid Receptors on Neurobehaviors

  • 발행 : 2003.04.01
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초록

1. Stimulation of dopaminergic system by morphine was abolished in ${\mu}$-opioid receptor knockout mice. 2. Dopaminergic stimulation by opioid agonists, morphine, DPDPE, and U50488, acts independently. 3. Loss of ${\mu}$-opioid receptors is more sensitive to the response of NMDA-induced convulsion and increase in the expression of mRNA for NMDA receptors.

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