한국막학회:학술대회논문집 (Proceedings of the Membrane Society of Korea Conference)
- 한국막학회 2003년도 The 4th Korea-Italy Workshop
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- Pages.61-64
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- 2003
OPTICAL RESOLUTION OF $\alpha$ -AMINO ACIDS USING ENANTIOSELECTIVE MEMBRANES
- Jonggeon Jegal (Membrane and Separation Research Center, Korea Research Institute of Chemical Technology) ;
- Kim, Jang-Hoon (Membrane and Separation Research Center, Korea Research Institute of Chemical Technology) ;
- Kim, Jee-Hye (Membrane and Separation Research Center, Korea Research Institute of Chemical Technology) ;
- Lee, Kew-Ho (Membrane and Separation Research Center, Korea Research Institute of Chemical Technology)
- 발행 : 2003.07.01
초록
Optical resolution of a-amino acid (tryptophan and tyrosine) optical isomers was achieved by a pressure driven membrane separation process, using self-supporting crosslinked membranes base on polysaccharide with different swelling indices that ranged from 100 to 70%. The membranes prepared by casting and drying the polymer solution containing 5wt% acetic acid on an acryl plate followed by crosslinking with glutaraldehyde were characterized using such analytical methods as FTIR and swelling index measurements. On the way of separating the optical isomers, several experimental factors such as the concentration of the feed solutions, operating pressure and temperature, and degree of crosslinking of the membranes have been studied. When the chitosan membranes with 70% of swelling index were used , almost complete optical resolution was obtained; 97.92% of enantiomeric excess (ee %) and 2.26 g/
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