대한전기학회:학술대회논문집 (Proceedings of the KIEE Conference)
- 대한전기학회 2002년도 추계학술대회 논문집 전기물성,응용부문
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- Pages.60-63
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- 2002
Study on Bead-based Microbiochip and Analytical System for Protein Detection
- Kim, Min-Soo (School of Electrical Engineering, Seoul National University) ;
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Chung, Woo-Jae
(School of Chemical Engineering, Seoul National University) ;
- Cho, Su-Hyung (School of Chemical Engineering, Seoul National University) ;
- Park, Sung-Soo (School of Chemical Engineering, Seoul National University) ;
- Kim, Byung-Gee (School of Chemical Engineering, Seoul National University) ;
- Lee, Young-Sik (School of Chemical Engineering, Seoul National University) ;
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Kim, Yong-Kweon
(School of Electrical Engineering, Seoul National University)
- 발행 : 2002.11.09
초록
This paper presents bead-based microbiocihps to detect and separate target proteins. Micro beads coated with capture proteins were introduced into a microchamber, and target proteins flowing across the chamber were bound and concentrated. The chip was connected with an external fluid system. Bead surfaces were double-coated with photo-cleavable linkers and capture proteins. The proteins bound on the beads were photo-separated under UV irradiation, and excited to be measured in fluorescence.
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