대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Iontophreotic delivery of vitamine-C-2-phosphate

  • Kim, Su-Youn (College of Pharmacy. Sookmyung Women′s University) ;
  • Oh, Seaung-Youl (College of Pharmacy. Sookmyung Women′s University)
  • 발행 : 2002.10.01
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초록

In order to develope an optimum formulation for iontophoretic delivery of vitamine-C-2 phosphate. we have prepared 3 different formulations using hydrophilic polymers, such as poloxamer, carbo pol and HPMC and iontophoretic flux through skin from these hydrogel formulations was carried out. The effect of current density, drug concentration and current profile on flux was investigated. In-vitro flux study was performed at 36.5$^{\circ}C$, using side-by-side diffusion cell. Full-thickness hairless mouse skin was used for this work. (omitted)

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