Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Preparation and Evaluation of Methacrylate copolymer Microspheres of Piroxicam

  • Yang, Jae-Heon (College of Pharmacy, Woosuk University) ;
  • Kim, Young-Il (Pharmaceutical engineering department Konyang University) ;
  • Chung, Kyu-Ho (Pharmaceutical engineering department Konyang University) ;
  • Kim, Dae-Sub (Pharmaceutical engineering department Konyang University)
  • Published : 2002.10.01
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Abstract

Microencapsulations of piroxicam using the mixture of Eudragit RS with RL or Eudragit L or E or S according to Eudragit RS were carried out. The Eudragit microspheres of piroxicam were prepared by solvent method. Piroxicam and Eudragit polymer were dissoved in methylene chloride and dispersed in 0.5% pOlyvinyl alcohol solution and solvent evaporated. The average diameters of various Eudragit microspheres were from 40 to 43${\mu}{\textrm}{m}$. A good and smooth surface of microspheres observed by SEM were shown in all type of microspheres. (omitted)

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