대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.398.2-398.2
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- 2002
Narrowbore high-performance liquid chromatographic method for the determination of cetirizine in plasma using column switching
- Hyun, Myung-Ja (College of Pharmacy, Seoul National University) ;
- Ban, Eunmi (College of Pharmacy, Seoul National University) ;
- Woo, Jong-Soo (Hanmi Pharmaceutical Co. Ltd) ;
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Kim, Chong-Kook
(College of Pharmacy, Seoul National University)
- 발행 : 2002.10.01
초록
A column switching HPLC assay was developed to allow the separation and quantitation of cetirizine in human plasma by ultraviolet (UV) detection. Plasma samples were prepared by liquid-liquid extraction. After drying, the residue was reconstituted in 20 mM phosphate buffer (pH 2.8) containing 15% acetonitrile. The samples were initially injected onto a clean-up Capcell Pak MF C18 column. (50 mm
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