Development of Quantitative Extraction Method of Amygdalin without Enzymatic Hydrolysis from Tonin(Persicae Semen) by High Performance Liquid Chromatography

  • Lee, Sang-Soo (Department of Oriental Pharmaceutical Sciences, Kyung Hee University) ;
  • Hwang, Eun-Young (Department of Oriental Pharmaceutical Sciences, Kyung Hee University) ;
  • Koh, Jung-A (Department of Oriental Pharmaceutical Sciences, Kyung Hee University) ;
  • Kim, Dong-Min (Department of Oriental Pharmaceutical Sciences, Kyung Hee University) ;
  • Lee, Je-Hyun (Department of Oriental Pharmaceutical Sciences, Kyung Hee University) ;
  • Lee, Yong-Moon (College of pharmacy Chungbuk National University) ;
  • Hong, Seon-Pyo (Department of Oriental Pharmaceutical Sciences, Kyung Hee University)
  • Published : 2002.10.01

Abstract

Tonin(Persicae Semen)is the herb medicine that cntains amygdalin as a major ingredient. Amygdalin in water is decomposed into benzaldehyde. HCN. and glucoseby emulsin. a hydrolysis enzyme intonin. A useful and practical method for the optimum extraction condition of amygdalin without enzymatic hydrolysis is required. The extraction yield of amygdalin of natural formula tonin was 0.1 % from crude powers. 1.4% from small pieces. 3.5% from half pieces and 2.4% from whole pieces. (omitted)

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