Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.381.3-382
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- 2002
Free radical scavenging phenolic compounds of the leaves of Juglans sinensis
- Kim, Mi-Hee (MRRC and college of Pharmacy, Wonkwang University) ;
- Ko, Eun-Kyung (MRRC and college of Pharmacy, Wonkwang University) ;
- Jun, Jung-Yang (MRRC and College of Pharmacy, Wonkwang University) ;
- Li-Xun (MRRC and College of Pharmacy, Wonkwang University) ;
- Oh, Myung-Hun (MRRC and College of Pharmacy, Wonkwang University) ;
- An, Nyeon-Hyoung (MRRC and College of Pharmacy, Wonkwang University) ;
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Kim, Youn-Chul
(MRRC and College of Pharmacy, Wonkwang University)
- Published : 2002.10.01
Abstract
Free radical-mediated cell damage and free radical attack on polyunsaturated fatty acids result in the formation of lipid radicals. These lipid radicals react readily with molecular oxygen to produce peroxy radicals responsible for initiating lipid peroxidation. The peroxidation of cellular membrane lipid can lead to cell necrosis and considered to be implicated in a number of pathophysiological conditions as well as in the toxicity of many xenobiotics. DPPH is known to abstract labile hydrogen and the ability to scavenge the DPPH radical is related to the inhibition of lipid peroxidation. (omitted)
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