대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.381.2-381.2
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- 2002
Free Radical Scavenging Compounds of Polygoni Multiflori Ramulus
- Li-Xun (MRRC and college of Pharmacy, Wonkwang University) ;
- Kim, Mi-Hee (MRRC and college of Pharmacy, Wonkwang University) ;
- Ko, Eun-Kyung (MRRC and college of Pharmacy, Wonkwang University) ;
- Jun, Jung-Yang (MRRC and college of Pharmacy, Wonkwang University) ;
- Oh, Myung-Hun (MRRC and college of Pharmacy, Wonkwang University) ;
- Shin, Hwa-Woo (MRRC and college of Pharmacy, Wonkwang University) ;
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Kim, Youn-Chul
(MRRC and college of Pharmacy, Wonkwang University)
- 발행 : 2002.10.01
초록
There is now increasing evidence that free radicals and active oxygen species are involved in a variety of pathological events. often associated with ageing. Free radical-mediated cell damage and free radical attack on polyunsaturated fatty acids result in the formation of lipid radicals. These lipid radicals react readily with molecular oxygen to produce peroxy radicals responsible for initiating lipid peroxidation. The peroxidation of cellular membrane lipid can lead to cell necrosis and considered to be implicated in a number of pathophysiological conditions as well as in the toxicity of many xenobiotics. (omitted)
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