Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Study on the Inhibition of Whole Blood Platelet-Aggregation and antioxidative effects from Rhus verniciflua Stokes

  • Jeon, Won-Kyung (Qualiti Control of Herbal Medicine Department, Korea Institute of Oriental Medicine) ;
  • Kim, Jung-Hee (Qualiti Control of Herbal Medicine Department, Korea Institute of Oriental Medicin) ;
  • Lee, A-Yeong (Qualiti Control of Herbal Medicine Department, Korea Institute of Oriental Medicin) ;
  • Kim, Ho-Kyoung (Qualiti Control of Herbal Medicine Department, Korea Institute of Oriental Medicine)
  • Published : 2002.10.01
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Abstract

Rhus verniciflua Stokes (RVS) is a widely used herbal plant with various biological properties. Our previous study using in vitro platelet aggregation in whole blood showed that ethyl acetate layer of RVS had strong anti-aggregatory activity. In this study. to investigate the anti-aggregatory activity and antioxidative effects of RVS ethyl acetate layer. the layer was subsequently fractionated by ODS columm chromatograph (50% MeOH). As a result. the fraction 3 was most inhibited the aggregation of platelet in rat whole blood induced by thrombin and all fraction of RVS was detected strong antioxidative effect. (omitted)

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