Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
- /
- Pages.378.1-378.1
- /
- 2002
Xanthorrhizol inhibits pro-inflammatory mediators in mouse macrophage cells
-
Min, Hye-Young
(College of Pharmacy. Ewha Womans University)
;
- Park, Hyen-Joo (College of Pharmacy. Ewha Womans University) ;
- Park, Eun-Jung (College of Pharmacy. Ewha Womans University) ;
- Park, Kwang-Kyun (College of Dental Medicine Yonsei University) ;
- Chung, Won-Yoon (College of Dental Medicine Yonsei University) ;
- Hwang, Jae-Kwan (Bioproducts Research Center, Yonsei University) ;
-
Lee, Sang-Kook
(College of Pharmacy. Ewha Womans University)
- Published : 2002.10.01
Abstract
Prostaglandins (PGs) and nitric oxide (NO) are essential to maintain homeostasis and defensa systems in human beings. However. overproduced PGs and NO by inducible cyclooxygenase (COX-2) and inducible nitric oxide synthase (iNOS), respectively. cause tissue damages. chronic inflammation. and carcinogenesis. In this view. the potential COX-2 or iNOS inhibitors have been considered as anti-inflammatory or cancer chemopreventive agents. (omitted)
Keywords