Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.371.1-371.1
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- 2002
In vivo Antinociceptive and Anti-inflammatory Effect of the Two Triterpenes. Ursolic Acid and 23- Hydroxyursolic Acid. of Cussonia bancoensis
- Tapondjou L.A (Department of Chemistry Faculty of Science University of Dschang Cameroon) ;
- Choi, Jong-Won (College of Pharmacy, Kyungsung University) ;
- Lee, Kyung-Tae (College of Pharmacy, Kyunghee University) ;
- Jung, Hyun-Ju (Division of Applied Plant Sciences Sangji Uni) ;
- Park, Hee-Juhn (Division of Applied Plant Sciences Sangji Univ)
- Published : 2002.10.01
Abstract
Triterpenoids. Ursolic acid (1). 23-hydroxyursolic acid (2). and tormentic acid (3) were obtained by the hydrolysis of BuOH fraction of Cussonia bancoensis extract and further chromatographic isolation to test antinociceptive and anti-inflammatory effect of C. bancoensis (Aratiaceae). Compound 1 and 2 exhibited anti-nociceptive effects, which were determined by acetic acid-induced writhing test and hot plate test. However. the effect of tormentic acid was not significant (omitted)
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