Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
- /
- Pages.358.3-358.3
- /
- 2002
Selective Cytotoxicity of Novel Platinum(II) Complexes on Gastric Cancer Cell-Lines and Normal Kidney Cells
- Kim, Jung-Tae (College of Pharmacy and 1 School of Medicine. Kyung Hee University) ;
- Hong, Eon-Pyo (College of Pharmacy and 1 School of Medicine. Kyung Hee University) ;
- Rho, Young-Soo (College of Pharmacy and 1 School of Medicine. Kyung Hee University) ;
- Jung, Jee-Chang (College of Pharmacy and 1 School of Medicine. Kyung Hee University)
- Published : 2002.10.01
Abstract
We recently synthesized new platinum(II) complex analogs containing trans-1 and cis-l.2-diaminocyclohexane (DACH) as carrier ligands and L -3-phenyllactic acid(PLA) as a leaving group. Our platinum-based drug discovery program has been aimed at developing drugs capable of diminishing toxicity and improving selective cytotoxicity. (omitted)
Keywords