Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.358.2-358.2
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- 2002
In vitro Antitumor Activity and Nephrotoxicity of Pt(II) Complexes Containing Diaminocyclohexane
- Hong, Eon-Pyo (College of Pharmacy and 1 School of Medicine. Kyung Hee University) ;
- Rho, Young-Soo (College of Pharmacy and 1 School of Medicine. Kyung Hee University) ;
- Jung, Jee-Chang (College of Pharmacy and 1 School of Medicine. Kyung Hee University)
- Published : 2002.10.01
Abstract
Platinum(II) coordination complex(cisplatin) has been currently used as one of the most effective compounds in the treatment of various solid tumors. However. its use has been limited by severe side effects such as renal toxicity. Our platinum-based drug discovery program has been aimed at developing drugs capable of diminishing toxicity and improving selective cytotoxicity. (omitted)
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