Synthesis of Selenoflavonoid and Selenoisoflavonoid.

  • Kim, Dong-Myung (Department of Pharmaceutical Science Graduate School Kyung Hee University) ;
  • Jeong, Jin-Hyun (Department of Pharmaceutical Science Graduate School Kyung Hee University)
  • Published : 2002.10.01

Abstract

Heterocyclic compounds with oxygen atoms are known to have potent biological effect. The flavonoids. isoflavonoids. and coumarins which form the bulk of these compounds are very polar and have limited use as drugs which have to pass through membranes. The non-polar property is increased by exchange oxygen to selenium as a part of heterocyclic compound. Our group is focused on synthesizing selenoheterocyclic compound with the above property. (omitted)

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