Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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The modulating activity of Ginsan on radiation-induced disturbance of antioxidant defense systems

  • Son, Soo-Jung (Laboratory of Immunology, Korea Cancer Center Hospital) ;
  • Kim, Chan-Wha (Laboratory of Biopharmaceutical Processes, Korea University) ;
  • Yun, Yeon-Sook (Laboratory of Biopharmaceutical Processes, Korea University)
  • Published : 2002.10.01
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Abstract

Ginsan, a polysaccharide extracted from Panax ginseng. was earlier scrutinized for a biological-response modifier. We further studied the protective and restorative activity of Ginsan against sublethal dose irradiation owing to increase production of endogenous hematopoietic growth factors such as IL-1. TNF-${\alpha}$. IL-6, GM-CSF. Which induce strong redox-emzyme elevation. Exposing to radiation induces reactive oxygen species (ROS). which play an important causative role in radiation damage. (omitted)

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