Effects of Platycodi Radix on dimethylnitrosamine-induced hepatic fibrosis in rats

  • Lee, Kyung-Jin (Department of Biology, Chonnam National University, Kwangju) ;
  • Choi, Chul-Yung (Department of Pharmacy and Research Center for Proteineous Materials, Chosun University, Kwangju. Korea) ;
  • Jeong, Hye-Gwang (Department of Pharmacy and Research Center for Proteineous Materials, Chosun University, Kwangju. Korea)
  • Published : 2002.10.01

Abstract

Herbal medicines are increasingly being utilized to treat a wide variety of disease processes. We previously reported that aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK). had hepatoprotective effects against acetaminophen induced liver injury. In the present study, we assayed the preventive and therapeutic effects of CK on experimental hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats. (omitted)

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