The Screening of Hepatic Functional Improvement. Liver Protection and Antifibrotic Effect from Dried Extracts of Concha Cipangopaludinae

  • Kim, Hee-Seok (Professional Graduate School of Oriental Medicine Wonkwang University) ;
  • Bae, Heung-Mo (Dept. of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicin) ;
  • Kim, Eun-Sook (Dept. of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicin) ;
  • Kim, Jin-Sook (Dept. of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicin) ;
  • Kim, Ki-Young (Dept. of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine)
  • Published : 2002.10.01

Abstract

Oxidative stress and its consequent lipid peroxidation exert harmful effects, which have been currently involved in the generation of carbon tetrachloride(CC14)-induced fibrosis(cirrhosis). In this study, it was investigated whether dried extract of 田螺(Concha Cipangopaludinae: CC) is liver functional improvement, antioxidative and antifibrotic effect under the liver fibrotic(cirrhotic) condition by CC14 administration. The female Sprague-Dawley rats were divided into 3 groups(Normal, AC, AC-CC), and were observed for 3 weeks. (omitted)

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