Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

The effects of extremely low frequency magnetic field on bicuculline, picrotoxin, NMDA-induced seizures in mice

  • Sung, Ji-Hyun (Department of Pharmacology, College of Pharmacy. Chung Ang University) ;
  • Jeong, Ji-Hoon (Department of Pharmacology, College of Pharmacy. Chung Ang University) ;
  • Kim, Jeong-Soo (Department of Pharmacology, College of Pharmacy. Chung Ang University) ;
  • Kum, Chan (Department of Pharmacology, College of Pharmacy. Chung Ang University) ;
  • Park, Sun-Young (Department of Pharmacology, College of Pharmacy. Chung Ang University) ;
  • Sohn, Uy-Dong (Department of Pharmacology, College of Pharmacy. Chung Ang University)
  • Published : 2002.10.01
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Abstract

Some experiments have been reported that magnetic fields can cause the change of numerous neurotransmitters including excitatory and inhibitory transmitters, which are involved in seizures. In this study we aimed to examine the effect of extremely low frequency magnetic field (ELF-MF) on the sensitivity of seizure response to bicuculline, picrotoxin and NMDA in mice. Mouse were exposed to sham or 20 G ELF-MF for 24 hours and then convulsants were administered i.p. at various doses. (omitted)

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