Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.270.2-270.2
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- 2002
Comparative Studies of Molecular Mechanisms of Dopamine D2 and D3 Receptors for the Activation of Extracellular Signal Regulated Kinase 1/2 in HEK-293 cells
- Cheong, Da-Woon (Pharmacology lab. College of Pharmacy, Chonnam National University) ;
- Cho, Choon-Sil (Pharmacology lab. College of Pharmacy, Chonnam National University) ;
- Kim, Hyun-Ju (Pharmacology lab. College of Pharmacy, Chonnam National University) ;
- Kim, Kyeong-Man (Pharmacology lab. College of Pharmacy, Chonnam National University)
- Published : 2002.10.01
Abstract
Dopamine D2 and D3 receptors (D2R and D3R) belong to pharmacological D2R family and share similar structural and functional characteristics. Elucidation of their differential functional characteristics is important for understanding their roles in brain. ERK1/2 was chosen as an example of signaling component of D2R and D3R and systemic studies were conducted to understand the regulatory mechanisms on ERK1/2 activation. (omitted)
Keywords