Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.265.1-265.1
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- 2002
The anti-inflammatory activity of Kalopanax pictus bark extract (IV). Antirheumatic activity of kalopanaxsaponin A methyl ester
- Li, Da-Wei (Natural Product Research Institute, Seoul National University) ;
- Hyun, Jin-Ee (College of Pharmacy, Duksung Women′s University) ;
- Jeong, Choon-Sik (College of Pharmacy, Duksung Women′s University) ;
- Kim, Yeong-Shik (College of Pharmacy, Duksung Women′s University) ;
- Lee, Eun-Bang (College of Pharmacy, Duksung Women′s University)
- Published : 2002.10.01
Abstract
In the previous study. we isolated kalopanaxsaponin A and pictoside A from the EtOAc fraction of Kalopanax pictus extract. In the present study, the BuOH fraction of K pictus extract was hydrolyzed by alkali and antirheumatic effect of the fraction was evaluated. It was found that the hydrolysate of the BuOH fraction showed inhibition of adjuvant-induced arthritis in rats. Of the EtOAc and BuOH fractions of the hydrolysate, only the former exhibited anti-arthritic activity. (omitted)
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