Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Protective effect of metabolized Yangguksanwha - tang on Hypoxia/Reperfusion induced-PC12 cell damage

  • Lee, Eun-Soo (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Kim, Kun-Tae (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Park, Ji-Ho (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Kang, Chul-Hun (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Sohn, Nak-Won (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Soh, Yun-Jo (Dept Neuroscience, Graduate School of East-West Medical Science, Kyung Hee University)
  • Published : 2002.10.01
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Abstract

This research was performed to investigate the protective effect of Yangguksanwha-tang(YST) agaist ischemic damage in PC 12 cells. To elucidate the mechanism of the protective effect of YST on ischemic insult. cell viability and changes in activities of Superoxide dismutase. Glutathione Peroxidase. Catalase. capase 3 and the production of Malondialdehyde were observed after treating PC12 cells with YSt which was metabolized by rat liver homogenate. (omitted)

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