Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Inhibitory Effect of Luteolin on $TNF-{\alpha}-Stimulated$ IL-8 Secretion from Intestinal Epithelial Cells

  • Kim, Jin-Ah (Department of Oriental Pharmacy, College of Pharmacy) ;
  • Kang, Ok-Hwa (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Baek, Ok-Seon (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Choi, Suck-Chei (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Kim, Tae-Hyun (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Seo, Geom-Seog (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Nah, Yong-Ho (Department of Internal Medicine, School of Medicine, Wonkwang University) ;
  • Lee, Young-Mi (Department of Internal Medicine, School of Medicine, Wonkwang University)
  • Published : 2002.10.01
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Abstract

Intestinal epithelial cells can produce cytokines and chemokines that play an important role in the mucosal immune response. Regulation of this secretion is important to prevent inflammatory tissue damage. Lonicera japonica have been shown to inhibit inflammation. We tested the effect of luteolin, a major ingredient of Lonicera japonica, on TNF-${\alpha}$-stimulated IL-8 secretion from lntestinal epithelial cells. (omitted)

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