Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.234.2-235
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- 2002
Simultaneous Profiling Analysis of Urinary Organic Acids and Amino Acids by Gas Chromatography and Gas Chromatography-Mass Spectrometry for Biochemical Diagnosis of Inherited Metabolic Disorders
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Paik, Man-Jeong
(College of Pharmacy. Sungkyunkwan University)
;
- Lee, Yoon-Suk (Kyonggi Pharmaceutical Research Center) ;
- Lee, Hong-Jin (Hallym University Hospital) ;
- Kim, Sook-Za (Korea Genetic Research Center) ;
- Kim, Kyoung-Rae (Korea Genetic Research Center)
- Published : 2002.10.01
Abstract
An efficient method for the simultaneous profiling analysis of organic acids and amino acids combined with a simple graphic pattern recognition method was developed for more objective diagnosis of organic acidurias and amino acidurias. In this method, extractive ethoxycarbonly (EOC) reaction of amino and sufhydry groups with ethyl chloroformate was followed by methodime (MO) formation of carbonyl group in aqueous solution (omitted)
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