Chemopreventive and Chemoprotective Potential of Naturally Occurring and Synthetic Anti-inflammatory Agents

Chemoprevention, one of the most innovative and promising areas of cancer research, refers to the prevention of cancer through pharmacologic or nutritional intervention. Recently, considerable attention has been focused on the role of cyclooxygenase-2 (COX-2) in the carcinogenesis as well as inflammation. Inappropriate up-regulation of COX-2 is implicated in the pathophysiology of certain types of human cancers. (omitted)